Thursday, December 6, 2018

Specialty Intermediates: Pharmaceuticals intermediates and Agrochemical Products

“specialty intermediates” are the large and small fluorinated molecules that serve as building blocks for pharmaceutical and agrochemical products.


There aren’t many compounds found in nature that contain fluorine. So because of this, it may seem like a strange leap to use fluorinated molecules in drugs and pesticides. But the desirable properties of fluorinated molecules make them well worth the time and energy to develop. For example, fluorine itself has a high electronegative charge, high reactivity and at the same time C-F bond is very stable.
Introducing fluorine into a biologically active molecule during the structure-activity optimization process can influence parameters like:
  • Blocking metabolic deactivation
  • Transporting bioactive molecules from the application to the target site
  • Binding to a target enzyme
Producing fluorinated molecules is a highly specialized field, especially on the scale needed to produce pharma and agrochemical compounds.


AGC General Life Science division

For the those reasons, AGC recently established a new General Life Science division to focus on small molecule and large moleculde production. A lot of our products contain one or more fluorines. These products are used as active ingredients and advanced intermediates in pharma and agrochem industries.
Our specialty intermediates include:
  • Mono- and di-fluorinated heterocyclics
  • Methyl 2-fluoromethacrylate
  • Difluoro pyrazole acid
  • C3 compounds (amines, alcohols, chlorides, etc)
  • Metallocene co-catalysts (borate activators)

cGMP Contract Manufacturing

As a contract manufacturer, we can help pharmaceutical manufacturers reduce costs and accelerate their product development and commercialization. We manufacture under cGMP conditions and our facilities undergo the corresponding FDA inspections on your request. Our multiple production sites allow us to achieve risk diversification and reliable supply to the needs of our global customers.
Call us today to discuss your specialty intermediate needs or click herehttp://www.ganeshremedies.com/speciality-fine-chemicals to view our product line.


PRODUCTS


SPECIALITY FINE CHEMICALS

Cyclopropanecarbonyl chloride4023-34-1Agrochemicals
1,8-Diaminooctane373-44-4Polymer Additives
Chlorocyclohexane542-18-7Agrochemicals
4-(2-Chloroethyl)morpholine hydrochloride3647-69-6Agrochemicals
Methyl cyclopropanecarboxylate2868-37-3Inhibitor Synthesis



PHARMACEUTICAL API DRUG INTERMEDIATES MANUFACTURING COMPANY

Bis(2-chloroethyl)amine hydrochloride821-48-7Aripiprazole, Batoprazine, Cyclophosphamide, Eltoprazine hydrochloride, Estramustine phosphate, Ifosfamide, Itraconazole, Ketoconazole, Lensiprazine, Naluzotan, Trazodone
Sodium bis(trimethylsilyl)amide solution1070-89-9Fluoratec, Tipranavir
2-(Diethylamino)ethyl Chloride Hydrochloride869-24-9Amiodarone, Bietaserpine, Butetamate, Camylofin, Ciclonium bromide, Clomifene, Cloricromen, DEA Dextran, Dimazole, Etafenone, Etamiphylline, Fenoxedil, Flurazepam, Gallamine triethiodine, Imolamine, Isothipendyl, Methadone, Myrtecaine, Naftidrofuryl, Oxitefonium bromide, Penthienate methobromide, Phenglutarimide, Promethazine, Propoxycaine, Proxymetacaine, Tiamulin, Tibezonium iodide, Tiropramide
4-Chloro-4′-fluorobutyrophenone3874-54-2Benperidol, Bromperidol, Droperidol, Fluanisone, Haloperidol, Melperone, Moperone, Pipamperone, Primaperone, Spiperone, Timiperone, Trifluperidol
2-(Dimethylamino)ethyl chloride hydrochloride4584-46-7Bephenium hydroxynaphthoate, Binedaline, Brompheniramine, Captodiame, Carbinoxamine, Chlorphenamine, Chlorphenoxamine, Clomiphene, Cyclopentolate, Dibenzepin, Diltiazem, Dimetindene, Doxylamine, Ethohptazine, Itopride hydrochloride, Meclofenoxate, Mepyramine, Moxisylyte, Normethadone, Noxiptiline, Pheniramine, Phenyltoloxamine, Tamoxifen, Toremifene, Trimethobenzamide, Tripelennamine, Zotepine
Diphenylacetonitrile86-29-3Aminepentamide Sulphate, Diphenoxylate, Diphenylacetaldehyde, Doxapram, Loperamide, Methadone
Dinitolmide148-01-6Antiprotozoan
Trityl chloride76-83-5Cefotaxime, Ceftazidime, Indeloxacine, Losartan potassium, Remoxiprode, Zidovudine
Cyclopropanecarbonyl Chloride4023-34-1Buprenorphine, Naltrexone, Prasugrel, Prazepam
Cyclopropanecarboxylic acid1759-53-1Prasugrel
2-Furoyl chloride527-69-5Ceftiofur, Diloxanide furoate, Furalaxyl, Mometasone furoate, Prazosin, Quinfamide, Terazosin
1-(2-Chloroethyl)piperidine hydrochloride2008-75-5Cloperastine, Fenpiverinium bromide, Pitofenone, Raloxifene
2-Diethylaminoethanethiol hydrochloride1942-52-5Desvenlafaxine
3-Dimethylamino-2-methylpropyl chloride hydrochloride4261-67-0Cyamepromazine, Levomepromazine, Promazine
3-(Dimethylamino)propyl chloride hydrochloride5407-04-5Acepromaxine, Amitriptyline, Bencyclane, Benzydamine, Chlorpromazine, Citalopram, Clomiphene, Clomipramine, Dibenzepin, Dimetacrine, Imipramine, Promazine, Prothipendyl, Triflupromazine
2-(Diisopropylamino)ethyl chloride hydrochloride4261-68-1Diisopromine, Disopyramide, Isopropamide iodide, Itopride hydrochloride
2-(Dimethylamino)isopropyl chloride hydrochloride4584-49-0Isothipendyl, Methadone, Promethazine
Cyclohexanecarbonyl chloride2719-27-9Praziquantel
2-Chloroethylamine hydrochloride870-24-6Ifosfamide
2-Methoxyphenothiazine1771-18-2Levomepromazine, Methotrimeprazine, Methoxypromazine
4-Chlorobutyryl chloride4635-59-0Mitomycin, Pyrazinamide
3-(Dibutylamino)propyl Chloride Hydrochloride115555-77-6Dronedarone
4-(2-Chloroethyl)morpholine hydrochloride3647-69-6Floredil, Morclofone, Nimorazole, Pholcodine
Cyclopropanecarbonitrile5500-21-0Pazufloxacin
Methyl cyclopropanecarboxylate2868-37-3Prasugrel
Cyclopropanecarboxamide6228-73-5Prasugrel
2-Furoic acid88-14-2Ceftiofur, Prazosin
1-(2-Chloroethyl)pyrrolidine hydrochloride7250-67-1Nafoxidine
1-Benzo[b]thien-4-yl-piperazine Monohydrochloride913614-18-3Brexpiprazole
7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone129722-34-5Aripiprazole, Brexpiprazole
Tyramine Hydrochloride60-19-5Tryptamine
1,2-Cyclohexanedicarboxylic acid1687-30-5Lurasidone
Dibenzosuberone1210-35-1Amitriptyline
Methyl 4-chlorobutyrate3153-37-5Prasugrel

No comments:

Post a Comment